منابع مشابه
Validation of Octanoate Breath Test for Measuring Gastric Emptying in Rats
BACKGROUND/AIMS Lack of simple and repeatable tests hampers gastric emptying studies in rats. The aim of this study was to adapt the (14)C-octanoate solid gastric emptying breath test for application in rats, and to validate it against radioscintigraphic method. METHODS After ingestion of a meal containing 3 mCi (99m)Tc and 2 µCi (14)C-octanoate, 23 male Wistar rats were placed on a gamma cam...
متن کاملDual role of mosapride citrate hydrate on the gastric emptying evaluated by the breath test in conscious rats.
Mosapride citrate hydrate (mosapride) has been known to act as a 5-HT4 agonist and to enhance gastric emptying. However, its mode of action, such as time course and dosage effect, on gastric emptying has not been clarified. This study aimed to clarify these points by the breath test using [1-(13)C]acetic acid in conscious rats. Mosapride significantly and dose-dependently enhanced the gastric e...
متن کامل13C-sodium acetate breath test for evaluation of gastric emptying times in dogs with gastric dilatation-volvulus.
OBJECTIVE The aim of the study was to assess solid phase gastric emptying via non-invasive 13C-sodium acetate breath test in large breed dogs with or without gastric dilatation-volvulus (GDV). MATERIAL AND METHODS Dogs were recruited into one of the following groups: group 1 = healthy large breed dogs with no history of GDV, group 2 = dogs that underwent elective abdominal surgery for reasons...
متن کاملAssessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test.
Gastric emptying studies in mice have been limited by the inability to follow gastric emptying changes in the same animal since the most commonly used techniques require killing of the animals and postmortem recovery of the meal(1,2). This approach prevents longitudinal studies to determine changes in gastric emptying with age and progression of disease. The commonly used [(13)C]-octanoic acid ...
متن کاملBayesian Hierarchical Methods to Interpret the 13C-Octanoic Acid Breath Test for Gastric Emptying
BACKGROUND The (13)C-octanoic acid breath test is a convenient method for assessing gastric emptying (GE). Success depends on obtaining a well-characterized time profile of the excretion of label in breath, which may not be the case if GE is delayed. AIMS To use Bayesian techniques in conjunction with hierarchical modelling as a method to increase the success of the modelling process. METHO...
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ژورنال
عنوان ژورنال: Journal of Neurogastroenterology and Motility
سال: 2013
ISSN: 2093-0879,2093-0887
DOI: 10.5056/jnm.2013.19.2.171